Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398847 | 0.99 | SIGMAR1 (0.56) | SIGMAR1CCR3HRH3HTR7ALDH1A1 | |
| SCHEMBL7401339 | 0.99 | SIGMAR1 (0.56) | SIGMAR1CCR3HRH3HTR7ALDH1A1 | |
| SCHEMBL7396651 | 0.99 | SIGMAR1 (0.56) | SIGMAR1CCR3HRH3HTR7ALDH1A1 | |
| SCHEMBL7449796 | 0.87 | SIGMAR1 (0.74) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7444410 | 0.85 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7451916 | 0.85 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7444256 | 0.85 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7437079 | 0.85 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7449513 | 0.85 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 | |
| SCHEMBL7446629 | 0.85 | SIGMAR1 (0.72) | SIGMAR1CCR3HRH3MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024390-A1 | NOVEL PHENYL(-ALKYL/ALKOXY)-1-AMINOALKYL-SUBSTITUTED PIPERIDINES AND PYRROLIDINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-09-14 | — | — | WO | disclosed |