SCHEMBL7401102

SCHEMBL7401102

CC1(C)Oc2cc3nonc3cc2C2OC21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8442759 0.80
SCHEMBL9224781 0.76 GRIA2 (0.37)
SCHEMBL2878172 0.75 PDGFRB (0.39) IDO1
SCHEMBL2891167 0.75 CYP1A2 (0.37) IDO1
SCHEMBL3595692 0.75 CYP1A2 (0.38) IDO1
SCHEMBL482485 0.75 ABCC9 (0.37) IDO1
SCHEMBL482676 0.75 ABCC9 (0.37) IDO1
SCHEMBL7402368 0.73 ABCC9 (0.32)
SCHEMBL2869264 0.72 KDM4E (0.37)
SCHEMBL2877929 0.72 KDM4E (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919806-A 8-AMINOPYRANO(2.3-F)BENZO-OXADIAZOLES, THIADIAZOLES AND TRIAZOLES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-07-06 US disclosed
EP-0541807-B1 NOVEL BENZOPYRAN DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 1997-12-17 EP disclosed
WO-1996034871-A1 BENZOPYRAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1996-11-07 WO disclosed
EP-0693283-A1 HEART FAILURE REMEDY NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-01-24 EP disclosed
US-5412117-A Potassium channel activators, antiasmatics, antiepileptics CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1995-05-02 US disclosed
EP-0409165-B1 Process for the optical resolution of pyranobenzoxadiazole compounds NISSAN CHEMICAL IND LTD (JP) 1995-04-19 EP disclosed
US-5319089-A Forming diastereomeric salt; solvating in ketone solvent; separation; removing solvent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1994-06-07 US disclosed
EP-0541807-A1 NOVEL BENZOPYRAN DERIVATIVE Chugai Seiyaku Kabushiki Kaisha (JP) 1993-05-19 EP disclosed
EP-0521936-A1 UNSATURATED N-BENZOXODIAZOPYRANYL LACTAMS, THEIR PRODUCTION AND USE BASF Aktiengesellschaft (DE) 1993-01-13 EP disclosed
US-5164509-A BENZODIAZOLO ANALOGS E. R. SQUIBB & SONS, INC. (US) 1992-11-17 US disclosed
EP-0488107-A2 Tricyclic benzodiazole analogs and their use in the treatment of cardiovascular disorders E.R. SQUIBB & SONS, INC. (US) 1992-06-03 EP disclosed
US-5097037-A Reaction with hydroxyphenoxypropionic acid NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1992-03-17 US disclosed
WO-1991014690-A1 UNSATURATED N-BENZOXODIAZOPYRANYL LACTAMS, THEIR PRODUCTION AND USE BASF AKTIENGESELLSCHAFT (DE) 1991-10-03 WO disclosed
EP-0409165-A2 Process for the optical resolution of pyranobenzoxadiazole compounds NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-01-23 EP disclosed