Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404076 | 1.00 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4220250 | 0.88 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7401508 | 0.88 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4219215 | 0.88 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6207307 | 0.88 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4219219 | 0.88 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4220253 | 0.88 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5731240 | 0.84 | SLC6A3 (0.59) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14173843 | 0.84 | SLC6A3 (0.59) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5731238 | 0.84 | SLC6A3 (0.59) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734385-A4 | SUBSTITUTED 2-CARBOXYALKYL-3-(FLUOROPHENYL)-8-(3-HALOPROPEN-2-YL) NORTROPANES AND THEIR USE AS IMAGING AGENTS FOR NEURODEGENERATIVE DISORDERS | GEN HOSPITAL CORP (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0734385-A1 | SUBSTITUTED 2-CARBOXYALKYL-3-(FLUOROPHENYL)-8-(3-HALOPROPEN-2-YL) NORTROPANES AND THEIR USE AS IMAGING AGENTS FOR NEURODEGENERATIVE DISORDERS | THE GENERAL HOSPITAL CORPORATION (US) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995011901-A9 | SUBSTITUTED 2-CARBOXYALKYL-3-(FLUOROPHENYL)-8-(3-HALOPROPEN-2-YL) NORTROPANES AND THEIR USE AS IMAGING AGENTS FOR NEURODEGENERATIVE DISORDERS | — | 1995-06-15 | — | — | WO | disclosed |
| WO-1995011901-A1 | SUBSTITUTED 2-CARBOXYALKYL-3-(FLUOROPHENYL)-8-(3-HALOPROPEN-2-YL) NORTROPANES AND THEIR USE AS IMAGING AGENTS FOR NEURODEGENERATIVE DISORDERS | THE GENERAL HOSPITAL CORPORATION (US) | 1995-05-04 | — | — | WO | disclosed |