Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7404001 | 0.99 | F10 (0.51) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7284365 | 0.96 | ITGB3 (0.47) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7283544 | 0.89 | F10 (0.51) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7405707 | 0.84 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7397069 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7280721 | 0.83 | S1PR1 (0.54) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7274316 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BHDAC1 | |
| SCHEMBL7395840 | 0.83 | ITGB3 (0.50) | ITGB3ITGA2B | |
| Methane SCHEMBL9145941 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7275468 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BF10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0825994-A1 | AMIDINE DERIVATIVES USEFUL AS ANTI-PLATELET AGGREGATION INHIBITORS AND VASODILATORS | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036639-A1 | AMIDINE DERIVATIVES USEFUL AS ANTI-PLATELET AGGREGATION INHIBITORS AND VASODILATORS | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |