Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76255 | 0.84 | FAAH (0.58) | KMT2AMEN1FAAHMAPK1CNR2 | |
| SCHEMBL117353 | 0.84 | FAAH (0.58) | KMT2AMEN1FAAHMAPK1CNR2 | |
| SCHEMBL75691 | 0.84 | FAAH (0.58) | KMT2AMEN1FAAHMAPK1CNR2 | |
| SCHEMBL74738 | 0.84 | FAAH (0.58) | KMT2AMEN1FAAHMAPK1CNR2 | |
| SCHEMBL76219 | 0.84 | FAAH (0.58) | KMT2AMEN1FAAHMAPK1CNR2 | |
| SCHEMBL785830 | 0.84 | FAAH (0.58) | KMT2AMEN1FAAHMAPK1CNR2 | |
| Hydrochloric Acid SCHEMBL17394702 | 0.83 | FAAH (0.56) | KMT2AMEN1FAAHMAPK1CNR2 | |
| Phosphoric Acid SCHEMBL4609086 | 0.79 | MEN1 (0.51) | KMT2AMEN1FAAHMAPK1CNR2 | |
| SCHEMBL29013598 | 0.79 | FAAH (0.51) | KMT2AMEN1FAAHMAPK1CNR2 | |
| SCHEMBL19847081 | 0.79 | FAAH (0.51) | KMT2AMEN1FAAHMAPK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997010243-A1 | 2-(PYRAZOL-5-YL-OXYMETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (US) | 1997-03-20 | — | — | WO | disclosed |