Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGAV | P06756 | 7/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 11/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417946 | 0.90 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6421398 | 0.90 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6419527 | 0.83 | ITGB3 (0.35) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7398477 | 0.80 | ITGB3 (0.44) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6419530 | 0.79 | ITGB3 (0.35) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6419206 | 0.77 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6419369 | 0.75 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7407629 | 0.75 | ITGB3 (0.37) | ITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL6419279 | 0.75 | ITGB3 (0.45) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6419440 | 0.74 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957917-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-0957917-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998014192-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-09 | — | — | WO | disclosed |