Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399322 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BHRH3KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL7395167 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BHRH3HRH1ALDH1A1 | |
| SCHEMBL7335413 | 0.78 | ITGB3 (0.52) | ITGB3ITGA2BHRH3KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL7399509 | 0.78 | ITGB3 (0.51) | ITGB3ITGA2BHRH3KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL9080887 | 0.75 | ITGB3 (0.58) | ITGB3ITGA2BHRH3HRH1ALDH1A1 | |
| SCHEMBL7398259 | 0.74 | ITGB3 (0.50) | ITGB3ITGA2BHRH3HRH1ALDH1A1 | |
| SCHEMBL7400055 | 0.72 | ITGB3 (0.54) | ITGB3ITGA2BHRH3HRH1ALDH1A1 | |
| SCHEMBL7327928 | 0.72 | HRH3 (0.59) | ITGB3ITGA2BHRH3HRH1ALDH1A1 | |
| SCHEMBL8602874 | 0.71 | ITGB3 (0.44) | ITGB3ITGA2BHRH3KCNH2HRH1 | |
| SCHEMBL7397816 | 0.70 | HRH3 (0.63) | ITGB3ITGA2BHRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5652242-A | 3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BURYIC ACID, AMIDE OR ESTER; INHIBITORS OF BINDING OF FIBRINOGEN TO GLYCOPROTEIN | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |