Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.41 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 2/20 | 0.39 |
| ▸ | PRKCH | P24723 | 2/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401923 | 1.00 | PRKCA (0.41) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7401925 | 1.00 | PRKCA (0.41) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7401771 | 1.00 | PRKCA (0.41) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7401776 | 1.00 | PRKCA (0.41) | PRKCAPRKCDPRKCGPRKCBPRKCH | |
| SCHEMBL7401654 | 0.82 | GRM2 (0.42) | PRKCAPRKCDGRM2TSHRHSD17B10 | |
| SCHEMBL7401650 | 0.82 | GRM2 (0.42) | PRKCAPRKCDGRM2TSHRHSD17B10 | |
| SCHEMBL7405665 | 0.82 | GRM2 (0.42) | PRKCAPRKCDGRM2TSHRHSD17B10 | |
| SCHEMBL7401646 | 0.82 | GRM2 (0.42) | PRKCAPRKCDGRM2TSHRHSD17B10 | |
| SCHEMBL7405668 | 0.82 | GRM2 (0.42) | PRKCAPRKCDGRM2TSHRHSD17B10 | |
| SCHEMBL7398691 | 0.81 | F2 (0.43) | PRKCAPRKCDPRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |