Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464731 | 0.84 | SNCA (0.58) | HTTMEN1NPC1KMT2ANSD2 | |
| SCHEMBL27491746 | 0.82 | MEN1 (0.50) | HTTMEN1NPC1KMT2ANSD2 | |
| SCHEMBL6424007 | 0.81 | NSD2 (0.43) | HTTMEN1NPC1KMT2ANSD2 | |
| SCHEMBL5118098 | 0.81 | NSD2 (0.63) | HTTMEN1NPC1KMT2ANSD2 | |
| SCHEMBL10788193 | 0.77 | LOXL2 (0.52) | HTTMEN1NPC1KMT2ANSD2 | |
| SCHEMBL14183081 | 0.77 | POLB (0.59) | HTTMEN1NPC1KMT2ANSD2 | |
| SCHEMBL20597769 | 0.77 | SNCA (0.51) | HTTMEN1NPC1KMT2ANSD2 | |
| SCHEMBL17701291 | 0.77 | NSD2 (0.48) | HTTMEN1NPC1KMT2ANSD2 | |
| SCHEMBL1009189 | 0.77 | NSD2 (0.45) | MEN1NPC1KMT2ANSD2SNCA | |
| SCHEMBL5317577 | 0.76 | NSD2 (0.61) | HTTMEN1NPC1KMT2ANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202988-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001010847-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | disclosed |