Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.54 |
| ▸ | ITGAV | P06756 | 17/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400841 | 0.98 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL7979245 | 0.84 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL7402534 | 0.83 | ITGB3 (0.40) | ITGB3ITGAVITGA2B | |
| SCHEMBL7980609 | 0.83 | ITGB3 (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL7400967 | 0.83 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL7404774 | 0.81 | ITGB3 (0.39) | ITGB3ITGAVITGA2B | |
| SCHEMBL7406835 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL8552051 | 0.80 | ITGB3 (0.62) | ITGB3ITGAVITGA2B | |
| SCHEMBL7404187 | 0.80 | ITGB3 (0.62) | ITGB3ITGAVITGA2B | |
| SCHEMBL7406107 | 0.80 | ITGB3 (0.46) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828737-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1996037492-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |