SCHEMBL7402018

SCHEMBL7402018

CCCCOC(=O)NNCCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.47
EPHX2 P34913 2/20 0.47
EPHX1 P07099 1/20 0.44
ALDH1A1 P00352 1/20 0.42
AKR1B1 P15121 1/20 0.41
PLA2G2A P14555 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7395822 0.89 ACHE (0.40) ACHEEPHX2EPHX1ALDH1A1AKR1B1
SCHEMBL473161 0.84 EPHX1 (0.53) ACHEEPHX2EPHX1ALDH1A1
SCHEMBL4736240 0.82 EPHX1 (0.56) ACHEEPHX2EPHX1ALDH1A1
SCHEMBL1161597 0.82 ACHE (0.65) ACHEEPHX2PLA2G2A
SCHEMBL473278 0.82 EPHX1 (0.56) ACHEEPHX2EPHX1ALDH1A1
Hydrochloric Acid SCHEMBL10476067 0.81 ACHE (0.62) ACHEEPHX2PLA2G2A
SCHEMBL855001 0.80 EPHX1 (0.52) ACHEEPHX1ALDH1A1
SCHEMBL16824229 0.79 EPHX1 (0.59) ACHEEPHX1ALDH1A1
SCHEMBL28079899 0.79 EPHX1 (0.61) ACHEEPHX1
SCHEMBL480293 0.77 ACHE (0.68) ACHEEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1255748-A1 BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-13 EP disclosed
WO-2001060813-A1 BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-08-23 WO disclosed