Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CCR3 | P51677 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402973 | 0.84 | GRIN2B (0.77) | GRIN1GRIN2BLMNAHTT | |
| SCHEMBL7404206 | 0.81 | GRIN1 (0.55) | GRIN1GRIN2BLMNAHTTCCR3 | |
| SCHEMBL7402824 | 0.81 | GRIN2B (0.55) | GRIN1GRIN2BLMNAHTTCCR3 | |
| SCHEMBL7404606 | 0.80 | HRH3 (0.48) | LMNAHTT | |
| SCHEMBL7399063 | 0.80 | GRIN1 (0.56) | GRIN1GRIN2BLMNAHTTCCR3 | |
| SCHEMBL7401789 | 0.80 | GRIN1 (0.56) | GRIN1GRIN2BLMNAHTTCCR3 | |
| SCHEMBL7404217 | 0.79 | GAA (0.70) | GRIN1GRIN2BLMNAHTT | |
| SCHEMBL7406534 | 0.79 | HTT (0.57) | GRIN1GRIN2BLMNAHTT | |
| SCHEMBL7253294 | 0.79 | GRIN1 (0.65) | GRIN1GRIN2BLMNAHTTCCR3 | |
| SCHEMBL7404039 | 0.79 | GRIN1 (0.55) | GRIN1GRIN2BLMNAHTTCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869791-A4 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0869791-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023214-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |