SCHEMBL7403304

SCHEMBL7403304

CC(C)c1cc(O)cc2c1C(=O)N(CBr)S2(=O)=O

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7009044 0.87 ELANE (0.63) ELANE
SCHEMBL7238810 0.81 ELANE (0.65) ELANE
SCHEMBL7280904 0.81 ELANE (0.56) ELANE
SCHEMBL7007242 0.80 ELANE (0.55) ELANE
SCHEMBL7336223 0.80 ELANE (0.54) ELANE
SCHEMBL7310086 0.77 ELANE (0.60) ELANE
SCHEMBL7382359 0.77 ELANE (0.80) ELANE
SCHEMBL8813362 0.76 ELANE (0.51) ELANE
SCHEMBL7296682 0.73 ELANE (0.66) ELANE
SCHEMBL7278118 0.73 ELANE (0.80) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750550-A RESPIRATORY SYSTEM DISORDERS SANOFI (FR) 1998-05-12 US disclosed
WO-1997010243-A1 2-(PYRAZOL-5-YL-OXYMETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANOFI (US) 1997-03-20 WO disclosed