SCHEMBL7336223

SCHEMBL7336223

CC(C)c1cc(O)cc2c1C(=O)N(C)S2(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ELANE P08246 19/20 0.54
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7009044 0.81 ELANE (0.63) ELANE
SCHEMBL8813362 0.81 ELANE (0.51) ELANE
SCHEMBL7403304 0.80 ELANE (0.62) ELANE
SCHEMBL7280904 0.74 ELANE (0.56) ELANECA9
SCHEMBL7007242 0.74 ELANE (0.55) ELANE
SCHEMBL7308324 0.72 ELANE (0.41) ELANE
SCHEMBL7382359 0.71 ELANE (0.80) ELANE
SCHEMBL8810134 0.70 ELANE (0.44) ELANE
SCHEMBL7012037 0.70 ELANE (0.41) ELANECA2CA9
SCHEMBL4907457 0.69 GABRA1 (0.50) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5385923-A Treatment of degenerative diseases STERLING WINTHROP INC. (US) 1995-01-31 US disclosed