Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 6/20 | 0.49 |
| ▸ | PLG | P00747 | 5/20 | 0.49 |
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506704 | 0.86 | CHEK2 (0.53) | CHEK2PLAUPLGF10F2 | |
| SCHEMBL7595573 | 0.79 | F2 (0.58) | PLAUPLGF10F2F7 | |
| SCHEMBL7406501 | 0.77 | F2 (0.53) | PLAUPLGF10F2F7 | |
| SCHEMBL7505853 | 0.76 | F10 (0.55) | PLAUPLGF10F2F7 | |
| SCHEMBL7403653 | 0.76 | F2 (0.49) | PLAUPLGF10F2F7 | |
| SCHEMBL7410068 | 0.76 | F2 (0.49) | PLAUPLGF10F2F7 | |
| SCHEMBL7403496 | 0.75 | F2 (0.46) | CHEK2PLAUPLGF10F2 | |
| SCHEMBL7511876 | 0.75 | F10 (0.50) | PLAUPLGF10F2F7 | |
| SCHEMBL7404382 | 0.75 | F2 (0.48) | PLAUPLGF10F2F7 | |
| SCHEMBL7403218 | 0.75 | F10 (0.49) | CHEK2F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |