Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.48 |
| ▸ | F10 | P00742 | 6/20 | 0.48 |
| ▸ | F7 | P08709 | 2/20 | 0.48 |
| ▸ | F9 | P00740 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 3/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406501 | 0.92 | F2 (0.53) | F2F10F7F9PRSS1 | |
| SCHEMBL7410068 | 0.90 | F2 (0.49) | F2F10F7F9PRSS1 | |
| SCHEMBL7403653 | 0.90 | F2 (0.49) | F2F10F7F9PRSS1 | |
| SCHEMBL7406090 | 0.82 | F10 (0.47) | F2F10F7F9PRSS1 | |
| SCHEMBL7595573 | 0.82 | F2 (0.58) | F2F10F7PRSS1PLAU | |
| SCHEMBL7405163 | 0.81 | F2 (0.53) | F2F10F7PRSS1PLAU | |
| SCHEMBL7405081 | 0.81 | F10 (0.44) | F2F10F7F9PRSS1 | |
| SCHEMBL7405066 | 0.81 | F2 (0.48) | F2F10F7F9PRSS1 | |
| SCHEMBL7450165 | 0.80 | HRH4 (0.50) | F2F10F7F9ALDH1A1 | |
| SCHEMBL7408467 | 0.80 | F10 (0.50) | F2F10F7PRSS1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |