Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 14/20 | 0.49 |
| ▸ | CASP6 | P55212 | 13/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404112 | 0.94 | CASP3 (0.48) | CASP3CASP8CASP6 | |
| SCHEMBL7408942 | 0.94 | CASP3 (0.49) | CASP3CASP8CASP6CASP1CASP9 | |
| SCHEMBL7412017 | 0.94 | CASP3 (0.48) | CASP3CASP8CASP6CASP1CASP9 | |
| SCHEMBL7406771 | 0.93 | CASP3 (0.47) | CASP3CASP8CASP6 | |
| SCHEMBL7409749 | 0.93 | CASP3 (0.47) | CASP3CASP8CASP6 | |
| SCHEMBL7402816 | 0.93 | CASP3 (0.48) | CASP3CASP8CASP6CASP1CASP9 | |
| SCHEMBL7454955 | 0.93 | CASP3 (0.50) | CASP3CASP8CASP6CASP1CASP9 | |
| SCHEMBL7463728 | 0.92 | CASP3 (0.50) | CASP3CASP8CASP6CASP1CASP9 | |
| SCHEMBL7406778 | 0.92 | CASP3 (0.47) | CASP3CASP8CASP6 | |
| SCHEMBL7454999 | 0.92 | CASP3 (0.48) | CASP3CASP8CASP6CASP1CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076968-A1 | MALONATES AS INHIBITORS OF THE ICE/CED-6 FAMILY OF CYSTEINE PROTEASES | NOVARTIS AG (CH) | 2002-10-03 | — | — | WO | disclosed |