SCHEMBL740422

SCHEMBL740422

CCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(CCC)cc4)c(F)c3)cc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.43
RARB P10826 3/20 0.43
RARA P10276 1/20 0.40
RARG P13631 1/20 0.40
SPHK2 Q9NRA0 7/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16258084 1.00 SPHK1 (0.43) SPHK1RARBRARARARGSPHK2
SCHEMBL16377238 0.97 SPHK1 (0.41) SPHK1RARBRARARARGSPHK2
SCHEMBL12920151 0.97 SPHK1 (0.41) SPHK1RARBRARARARGSPHK2
SCHEMBL17190571 0.96 SPHK1 (0.46) SPHK1RARBRARARARGSPHK2
SCHEMBL13471460 0.94 RARB (0.42) SPHK1RARBRARARARGSPHK2
SCHEMBL10943945 0.93 SPHK1 (0.42) SPHK1RARBSPHK2CYP3A4CYP2C9
SCHEMBL10943958 0.93 SPHK1 (0.42) SPHK1RARBSPHK2CYP3A4CYP2C9
SCHEMBL10948835 0.93 RARB (0.45) SPHK1RARBSPHK2CYP3A4CYP2C9
SCHEMBL8049989 0.93 RARB (0.45) SPHK1RARBSPHK2CYP3A4CYP2C9
SCHEMBL9662921 0.92 RARB (0.44) SPHK1RARBSPHK2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
EP-2669354-B1 Cyclohexene-3,6-diyl Compound, Liquid Crystal Composition and Liquid Crystal Display Device JNC CORP (JP) 2019-07-24 EP disclosed
US-20180187079-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-07-05 US disclosed
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-9963636-B2 Liquid crystal composition and liquid crystal display device using same DIC CORPORATION (JP) 2018-05-08 US disclosed
US-9938463-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2018-04-10 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-20090032771-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2009-02-05 US disclosed
US-7485351-B2 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 2009-02-03 US disclosed
US-20080303001-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2008-12-11 US disclosed
US-20080280071-A1 POLYMER/LIQUID CRYSTAL COMPOSITE AND LIQUID CRYSTAL ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2008-11-13 US disclosed
US-20080230746-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2008-09-25 US disclosed
US-20080083903-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2008-04-10 US disclosed
US-20080029736-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2008-02-07 US disclosed
US-20080029737-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2008-02-07 US disclosed
US-20080011984-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2008-01-17 US disclosed
US-20070290169-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 SPHK1 857/4885RARB 3196/4885RARA 3675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.