Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049989 | 1.00 | RARB (0.45) | RARBSPHK1SPHK2CYP3A4CYP2C9 | |
| SCHEMBL9662921 | 0.99 | RARB (0.44) | RARBSPHK1SPHK2CYP3A4CYP2C9 | |
| SCHEMBL10945641 | 0.95 | RARB (0.50) | RARBSPHK1SPHK2FFAR4 | |
| SCHEMBL10945649 | 0.95 | RARB (0.50) | RARBSPHK1SPHK2FFAR4 | |
| SCHEMBL9663403 | 0.95 | RARB (0.42) | RARBSPHK1SPHK2CYP3A4CYP2C9 | |
| SCHEMBL10943636 | 0.94 | RARB (0.49) | RARBSPHK1SPHK2FFAR4 | |
| SCHEMBL9664858 | 0.94 | RARB (0.46) | RARBSPHK1SPHK2CYP3A4CYP2C9 | |
| SCHEMBL9665285 | 0.94 | RARB (0.49) | RARBSPHK1SPHK2FFAR4 | |
| SCHEMBL10943630 | 0.94 | RARB (0.49) | RARBSPHK1SPHK2FFAR4 | |
| SCHEMBL740422 | 0.93 | SPHK1 (0.43) | RARBSPHK1SPHK2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4545922-A | Liquid crystalline fluorine-containing cyclohexylbiphenyls and dielectrics and electro-optical display elements based thereon | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-10-08 | — | — | US | disclosed |
| EP-0051738-B1 | CYCLOHEXYL-BIPHENYL DERIVATIVES THAT CONTAIN FLUOR, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4415470-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-11-15 | — | — | US | disclosed |