Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404618 | 0.91 | HPGD (0.43) | HRH4HPGDMGLLHTR2BALDH1A1 | |
| SCHEMBL7401784 | 0.86 | NPC1 (0.44) | HPGDHTR2BF10F9F2 | |
| SCHEMBL7404651 | 0.85 | MAPK14 (0.48) | HPGDLMNATSHRALDH1A1F10 | |
| SCHEMBL7408023 | 0.83 | LMNA (0.44) | HPGDMGLLHTR2BLMNATSHR | |
| SCHEMBL7406501 | 0.83 | F2 (0.53) | IDO1MAPTF10F9F2 | |
| SCHEMBL7403653 | 0.81 | F2 (0.49) | F10F9F2F7 | |
| SCHEMBL7410068 | 0.81 | F2 (0.49) | LMNAIDO1MAPTF10F9 | |
| SCHEMBL7404382 | 0.80 | F2 (0.48) | IDO1ALDH1A1MAPTF10F9 | |
| SCHEMBL7406090 | 0.78 | F10 (0.47) | HPGDALDH1A1F10F9F2 | |
| SCHEMBL7405081 | 0.77 | F10 (0.44) | F10F9F2F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |