Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 17/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359098 | 0.85 | NOTUM (0.54) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL22325390 | 0.84 | NOTUM (0.53) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL27818248 | 0.81 | NOTUM (0.50) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL26918079 | 0.80 | NOTUM (0.57) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL10447781 | 0.79 | NOTUM (0.78) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL18076592 | 0.79 | NOTUM (0.47) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL7090693 | 0.79 | NOTUM (0.47) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL76794 | 0.78 | NOTUM (0.64) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL17768008 | 0.76 | NOTUM (0.51) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL2627224 | 0.76 | NOTUM (0.64) | NOTUMKEAP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |