Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ITGAM | P11215 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | F3 | P13726 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400534 | 0.94 | ITGB3 (0.55) | ITGB3ITGA2BITGB2ITGAM | |
| Trifluoroacetic Acid SCHEMBL7400268 | 0.91 | ITGB3 (0.47) | ITGB3ITGA2BITGB2ITGAMF2 | |
| Trifluoroacetic Acid SCHEMBL7397995 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BITGB2ITGAMF2 | |
| SCHEMBL7405139 | 0.87 | ITGB3 (0.39) | ITGB3ITGA2BITGB2ITGAMF2 | |
| Trifluoroacetic Acid SCHEMBL7396061 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BITGB2ITGAMF2 | |
| SCHEMBL7395044 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BITGB2ITGAM | |
| SCHEMBL7404093 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7396412 | 0.80 | ITGB3 (0.51) | ITGB3ITGA2BF2 | |
| Trifluoroacetic Acid SCHEMBL7404770 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2BITGB2ITGAMF2 | |
| SCHEMBL7273726 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0715623-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | claimed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | claimed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | claimed |