Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 5/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438125 | 0.89 | GBA1 (0.48) | BCHEACHEGBA1SLC6A2SLC6A4 | |
| SCHEMBL7075735 | 0.89 | GBA1 (0.48) | BCHEACHEGBA1SLC6A2SLC6A4 | |
| SCHEMBL27739956 | 0.86 | REN (0.47) | BCHEACHEGBA1SLC6A2SLC6A4 | |
| SCHEMBL8172047 | 0.84 | BCHE (0.53) | BCHEACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2977281 | 0.84 | BCHE (0.44) | BCHEACHEGBA1SLC6A2SLC6A4 | |
| SCHEMBL4736581 | 0.83 | BCHE (0.57) | BCHEACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4736657 | 0.83 | BCHE (0.57) | BCHEACHESLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL1572929 | 0.81 | BCHE (0.56) | BCHEACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30456151 | 0.80 | BCHE (0.49) | BCHEACHEGBA1SLC6A2SLC6A4 | |
| SCHEMBL30287794 | 0.80 | BCHE (0.60) | BCHEACHESLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863903-A | ANTIDIABETIC AGENT | NOVO NORDISK A/S (DK) | 1999-01-26 | — | — | US | disclosed |
| EP-0749423-A1 | PIPERIDINES AND PYRROLIDINES | NOVO NORDISK A/S (DK) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024391-A1 | PIPERIDINES AND PYRROLIDINES | NOVO NORDISK A/S (DK) | 1995-09-14 | — | — | WO | disclosed |