Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CFTR | P13569 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12867382 | 0.85 | GAA (0.58) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL11795594 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL27275816 | 0.83 | GAA (0.51) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL27796104 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL3666380 | 0.81 | ABL1 (0.57) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL31743304 | 0.81 | GAA (0.50) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL21955060 | 0.81 | GAA (0.50) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL1553565 | 0.81 | KDM4E (0.51) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL2961456 | 0.81 | ABL1 (0.53) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL3970432 | 0.81 | GAA (0.50) | ALDH1A1HSD17B10CFTRGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |