Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407424 | 1.00 | PREP (0.55) | PREP | |
| SCHEMBL7413278 | 0.92 | — | — | |
| SCHEMBL7406047 | 0.92 | — | — | |
| SCHEMBL7511367 | 0.91 | ELANE (0.60) | — | |
| SCHEMBL7511361 | 0.91 | ELANE (0.60) | — | |
| SCHEMBL7405101 | 0.88 | PREP (0.54) | PREP | |
| SCHEMBL7401667 | 0.82 | ELANE (0.58) | — | |
| SCHEMBL7404559 | 0.78 | PREP (0.58) | PREP | |
| SCHEMBL7410346 | 0.76 | ELANE (0.58) | — | |
| SCHEMBL20678314 | 0.75 | PREP (0.71) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973775-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043975-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |