Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.52 |
| ▸ | F2 | P00734 | 4/20 | 0.52 |
| ▸ | F7 | P08709 | 3/20 | 0.52 |
| ▸ | PLG | P00747 | 5/20 | 0.44 |
| ▸ | PLAU | P00749 | 5/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406095 | 0.90 | F10 (0.48) | F10F2F7PLGPLAU | |
| SCHEMBL7447582 | 0.84 | F10 (0.52) | F10F2F7PLGPLAU | |
| SCHEMBL7407441 | 0.84 | F10 (0.57) | F10F2F7PLGPLAU | |
| SCHEMBL7407177 | 0.83 | F10 (0.64) | F10F2F7PLGPLAU | |
| SCHEMBL7408187 | 0.81 | F10 (0.58) | F10F2F7PLGPLAU | |
| SCHEMBL7404762 | 0.78 | F2 (0.52) | F10F2F7PLGPLAU | |
| SCHEMBL7404725 | 0.76 | F10 (0.52) | F10F2F7PLGPLAU | |
| SCHEMBL7401691 | 0.74 | F2 (0.46) | F10F2F7PLGPLAU | |
| SCHEMBL7477008 | 0.74 | F2 (0.53) | F10F2F7PLGPLAU | |
| SCHEMBL7405159 | 0.74 | F10 (0.55) | F10F2F7PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |