Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | F7 | P08709 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408187 | 0.93 | F10 (0.58) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7478941 | 0.84 | NPC1 (0.60) | RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL7404762 | 0.82 | F2 (0.52) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7478399 | 0.80 | F2 (0.47) | F2F10F7RAB9ANPC1 | |
| SCHEMBL7407177 | 0.80 | F10 (0.64) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7476301 | 0.75 | KLK1 (0.53) | F2F10F7RAB9ANPC1 | |
| SCHEMBL7407441 | 0.75 | F10 (0.57) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7479169 | 0.75 | F10 (0.71) | F2F10F7RAB9ANPC1 | |
| SCHEMBL7405290 | 0.74 | F10 (0.52) | F2F10F7TPSAB1PRSS1 | |
| SCHEMBL7477294 | 0.72 | APEX1 (0.44) | F2F10F7TPSAB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026933-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |