SCHEMBL7406013

SCHEMBL7406013

O=C1CC(C(Cl)(Cl)Cl)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8463244 1.00
SCHEMBL8673074 1.00
SCHEMBL8587350 0.79
SCHEMBL2877317 0.79
SCHEMBL1115349 0.74 SMN1; SMN2 (0.41)
SCHEMBL9515375 0.72
SCHEMBL8352516 0.72
SCHEMBL6422632 0.67 NR1I2 (0.32)
SCHEMBL10018502 0.67
SCHEMBL10018500 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291050-B Polymeric flame retardant mixtures 科莱恩塑料和涂料有限公司 2021-06-25 CN disclosed
US-20180346739-A1 POLYMERIC FLAME RETARDANT MIXTURES CLARIANT PLASTICS & COATINGS LTD (CH) 2018-12-06 US disclosed
EP-3380551-A1 POLYMERIC FLAME RETARDANT MIXTURES Clariant Plastics & Coatings Ltd (CH) 2018-10-03 EP disclosed
CN-108291050-A POLYMERIC FLAME RETARDANT MIXTURES 科莱恩塑料和涂料有限公司 2018-07-17 CN disclosed
WO-2017089293-A1 POLYMERIC FLAME RETARDANT MIXTURES CLARIANT INTERNATIONAL LTD (CH) 2017-06-01 WO disclosed
CN-101486692-B Preparation of optically pure (R)-4-trihalomethyl-2-heterocycle butanone FUDAN UNIVERSITY (CN) 2011-12-07 CN disclosed
CN-101486692-A Preparation of optically pure (R)-4-trihalomethyl-2-heterocycle butanone UNIV FUDAN (CN) 2009-07-22 CN disclosed
US-5977330-A AS HUMECTANTS FOR SKIN AND MUCOUS MEMBRANES; ANTIDEPOSIT AGENTS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-11-02 US disclosed
US-5708152-A DERIVATIVES AS HUMECTANTS AND ANTIDEPOSIT AGENTS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-01-13 US disclosed
US-5650270-A DETECTABLE SIGNALS FOR LABELS AND ANALYZING NORTHEASTERN UNIVERSITY (US) 1997-07-22 US disclosed
US-4681977-A REDUCTION OF TRICHLOROMETHYL COMPOUND WITH CHROMIUM SALT BASF AKTIENGESELLSCHAFT (DE) 1987-07-21 US disclosed
EP-0167097-A1 Process for preparing chloroolefins BASF Aktiengesellschaft (DE) 1986-01-08 EP disclosed
US-4495197-A N-Carboxyl-thienamycin esters and analogs thereof as anti-inflammatory agents MERCK & CO., INC. (US) 1985-01-22 US disclosed
US-4493839-A 1-Carbapenem-3-carboxylic esters as anti-inflammatory agents MERCK & CO., INC. (US) 1985-01-15 US disclosed
EP-0129136-A2 Antihypertensive composition MERCK & CO. INC. (US) 1984-12-27 EP disclosed
US-4472384-A INTERPHENYLENE 9-THIA-11-OXO-12-AZA PROSTANOIC ACID DERIVATIVE AND CARBOXYALKYLDIPEPTIDE MERCK & CO., INC. (US) 1984-09-18 US disclosed
US-4465687-A ANTIARTHRITIC AGENT, ENZYME INHIBITOR MERCK & CO., INC. (US) 1984-08-14 US disclosed
US-4390703-A Intermediates for the resolution of some interphenylene-9-thia-11-oxo-12-azaprostanoic acids MERCK & CO., INC. (US) 1983-06-28 US disclosed
US-4389525-A Process for the resolution of some interphenylene 9-thia-11-oxo-12-azaprostanoic acids MERCK & CO., INC. (US) 1983-06-21 US disclosed
US-4151279-A Fungicidal N-carbamyloxy-2,3-disubstituted 4-trihalomethyl-6-oxotetrahydro-1,3-oxazines CHEVRON RESEARCH COMPANY (US) 1979-04-24 US disclosed