⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406013 | 1.00 | — | — | |
| SCHEMBL8673074 | 1.00 | — | — | |
| SCHEMBL8587350 | 0.79 | — | — | |
| SCHEMBL2877317 | 0.79 | — | — | |
| SCHEMBL1115349 | 0.74 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL9515375 | 0.72 | — | — | |
| SCHEMBL8352516 | 0.72 | — | — | |
| SCHEMBL6422632 | 0.67 | NR1I2 (0.32) | — | |
| SCHEMBL10018502 | 0.67 | — | — | |
| SCHEMBL10018500 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10087547-A | — | — | None | — | — | JP | disclosed |
| EP-2595951-B1 | A PROCESS FOR THE PRODUCTION OF CARNITINE | LONZA AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| US-8563752-B2 | Process for the production of carnitine by cycloaddition | LONZA LTD. (CH) | 2013-10-22 | — | — | US | disclosed |
| US-20120022275-A1 | PROCESS FOR THE PRODUCTION OF CARNITINE BY CYCLOADDITION | LONZA LTD. (CH) | 2012-01-26 | — | — | US | disclosed |
| WO-2012010296-A1 | A PROCESS FOR THE PRODUCTION OF CARNITINE | LONZA LTD (CH) | 2012-01-26 | — | — | WO | disclosed |
| EP-2409965-A1 | A process for the production of carnitine by cycloaddition | Lonza Ltd. (CH) | 2012-01-25 | — | — | EP | disclosed |
| CN-101486692-B | Preparation of optically pure (R)-4-trihalomethyl-2-heterocycle butanone | FUDAN UNIVERSITY (CN) | 2011-12-07 | — | — | CN | disclosed |
| CN-101486692-A | Preparation of optically pure (R)-4-trihalomethyl-2-heterocycle butanone | UNIV FUDAN (CN) | 2009-07-22 | — | — | CN | disclosed |
| US-5977330-A | AS HUMECTANTS FOR SKIN AND MUCOUS MEMBRANES; ANTIDEPOSIT AGENTS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| JP-H1087547-A | PRODUCTION OF OPTICALLY ACTIVE SYNTHETIC INTERMEDIATE | NIPPON SODA CO LTD | 1998-04-07 | — | — | JP | disclosed |
| US-5708152-A | DERIVATIVES AS HUMECTANTS AND ANTIDEPOSIT AGENTS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0375611-B1 | ENANTIOMERIC SILANES, MODIFIED SUPPORT AND ITS USE | CIBA-GEIGY AG (CH) | 1993-04-07 | — | — | EP | disclosed |
| EP-0376883-B1 | ENANTIOMERIC SILANES, MODIFIED SUPPORT AND ITS USE | CIBA-GEIGY AG (CH) | 1993-04-07 | — | — | EP | disclosed |
| US-4997966-A | Chromatography, chemical condensation | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4997965-A | Chromatography | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0376883-A1 | Enantiomeric silanes, modified support and its use | CIBA-GEIGY AG (CH) | 1990-07-04 | — | — | EP | disclosed |
| EP-0375611-A1 | Enantiomeric silanes, modified support and its use | CIBA-GEIGY AG (CH) | 1990-06-27 | — | — | EP | disclosed |