Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.67 |
| ▸ | VPS4B | O75351 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 5/20 | 0.45 |
| ▸ | HTR1D | P28221 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408494 | 0.89 | HTR1F (0.58) | HTR1FSLC6A4HTR6HTR1BHTR1D | |
| SCHEMBL7403681 | 0.85 | HTR1F (0.56) | HTR1FSLC6A4BAZ2BHTR1BHTR1D | |
| SCHEMBL7417626 | 0.84 | HTR1F (0.55) | HTR1FSLC6A4HTR6BAZ2BHTR1B | |
| SCHEMBL6963427 | 0.84 | HTR1F (0.58) | HTR1FHTR1BHTR1DHTR1ADRD1 | |
| SCHEMBL7410109 | 0.84 | HTR1F (0.55) | HTR1FHTR6BAZ2BHTR1BHTR1D | |
| SCHEMBL6964061 | 0.84 | HTR1F (0.55) | HTR1FSLC6A4HTR6BAZ2BHTR1B | |
| Hydrochloric Acid SCHEMBL6959661 | 0.83 | HTR1F (0.54) | HTR1FSLC6A4HTR6BAZ2BHTR1B | |
| Iodide SCHEMBL6963382 | 0.83 | HTR1F (0.54) | HTR1FSLC6A4HTR6BAZ2BHTR1B | |
| Iodide SCHEMBL6963386 | 0.83 | HTR1F (0.54) | HTR1FSLC6A4HTR6BAZ2BHTR1B | |
| Hydrochloric Acid SCHEMBL7653861 | 0.83 | HTR1F (0.54) | HTR1FHTR6BAZ2BHTR1BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |