Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410366 | 1.00 | MAPK1 (0.59) | MAPK1ALDH1A1USP2TSHRLMNA | |
| SCHEMBL7407205 | 0.98 | MAPK1 (0.57) | MAPK1ALDH1A1USP2TSHRLMNA | |
| SCHEMBL32681951 | 0.92 | MAPK1 (0.49) | MAPK1ALDH1A1USP2TSHRLMNA | |
| SCHEMBL10602483 | 0.85 | ALDH1A1 (0.74) | MAPK1ALDH1A1USP2TSHRLMNA | |
| SCHEMBL3421776 | 0.85 | ALDH1A1 (0.74) | MAPK1ALDH1A1USP2TSHRLMNA | |
| SCHEMBL98282 | 0.85 | ALDH1A1 (0.74) | MAPK1ALDH1A1USP2TSHRLMNA | |
| SCHEMBL2871721 | 0.85 | ALDH1A1 (0.74) | MAPK1ALDH1A1USP2TSHRLMNA | |
| SCHEMBL929568 | 0.83 | ALDH1A1 (0.71) | MAPK1ALDH1A1USP2TSHRLMNA | |
| Hydrochloric Acid SCHEMBL4137591 | 0.83 | ALDH1A1 (0.71) | MAPK1ALDH1A1USP2TSHRLMNA | |
| SCHEMBL337085 | 0.82 | ALDH1A1 (0.70) | MAPK1ALDH1A1USP2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152326-A | AND CYCLIC HYDROXYIMIDES, INTERMEDIATES IN PREPARATION OF CYCLIC AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| US-4152326-A | AND CYCLIC HYDROXYIMIDES, INTERMEDIATES IN PREPARATION OF CYCLIC AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 1979-05-01 | — | — | US | disclosed |