Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 8/20 | 0.48 |
| ▸ | ACP3 | P15309 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407197 | 1.00 | MME (0.48) | MMEMMEL1ACP3ACE | |
| SCHEMBL7407909 | 0.88 | MME (0.57) | MMEMMEL1ACE | |
| SCHEMBL7407921 | 0.88 | MME (0.57) | MMEMMEL1ACE | |
| SCHEMBL7415381 | 0.85 | MMEL1 (0.50) | MMEMMEL1ACP3ACE | |
| SCHEMBL7415374 | 0.85 | MMEL1 (0.50) | MMEMMEL1ACP3ACE | |
| SCHEMBL7407171 | 0.83 | MME (0.50) | MMEACP3ACE | |
| SCHEMBL7407179 | 0.83 | MME (0.50) | MMEACP3ACE | |
| SCHEMBL7310766 | 0.80 | MME (0.48) | MMEMMEL1ACE | |
| SCHEMBL7310740 | 0.80 | MME (0.48) | MMEMMEL1ACE | |
| SCHEMBL7309981 | 0.78 | MMEL1 (0.59) | MMEMMEL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |