SCHEMBL7407304

SCHEMBL7407304

COCCN(CCOC)S(=O)(=O)c1ccc2c(c1)nc(Cc1nc3cc(C(=N)N)ccc3[nH]1)n2C

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
F2 P00734 11/20 0.44
ALDH1A1 P00352 1/20 0.41
PKM P14618 1/20 0.41
F10 P00742 5/20 0.41
KDM4E B2RXH2 1/20 0.39
TPSAB1 Q15661 3/20 0.38
PRSS1 P07477 2/20 0.38
PLG P00747 1/20 0.38
PLAU P00749 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
TPSD1 Q9BZJ3 1/20 0.38
TPSG1 Q9NRR2 1/20 0.38
F7 P08709 1/20 0.38
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7405869 0.85 F2 (0.49) F2F10TPSAB1PRSS1PLG
SCHEMBL7407336 0.80 F2 (0.47) F2PKMF10TPSAB1PRSS1
SCHEMBL7407314 0.79 KDM4E (0.44) ALDH1A1PKMF10KDM4ERECQL
SCHEMBL7409773 0.78 SMN1; SMN2 (0.47) F2ALDH1A1KDM4EKMT2ALMNA
SCHEMBL7405344 0.78 F2 (0.55) F2ALDH1A1PKMF10F7
SCHEMBL7406196 0.77 F10 (0.56) F2F10TPSAB1PRSS1PLG
SCHEMBL7406521 0.77 F2 (0.49) F2F10TPSAB1PRSS1PLG
SCHEMBL7404219 0.76 F10 (0.64) F2F10TPSAB1PRSS1PLG
SCHEMBL7402998 0.76 F10 (0.58) F2F10TPSAB1PRSS1PLG
SCHEMBL7410430 0.75 F2 (0.45) F2ALDH1A1KDM4ERECQLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999026932-A1 BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS AXYS PHARMACEUTICALS, INC. (US) 1999-06-03 WO disclosed