Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406521 | 0.85 | F2 (0.49) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL7405344 | 0.84 | F2 (0.55) | F2F10F7PKM | |
| SCHEMBL7410430 | 0.84 | F2 (0.45) | F2 | |
| SCHEMBL7405869 | 0.83 | F2 (0.49) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL7407304 | 0.80 | F2 (0.44) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL7407342 | 0.80 | CDK1 (0.45) | F2CDK1CDK2F10PRSS1 | |
| SCHEMBL7409773 | 0.77 | SMN1; SMN2 (0.47) | F2 | |
| SCHEMBL7403871 | 0.77 | F10 (0.46) | F2CDK1CDK2F10TPSAB1 | |
| SCHEMBL7406196 | 0.76 | F10 (0.56) | F2F10TPSAB1PRSS1PLG | |
| SCHEMBL7407064 | 0.76 | F10 (0.50) | F2CDK1CDK2F10TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |