SCHEMBL740740

SCHEMBL740740

CCOC(=O)CC(S)C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
ALDH1A1 P00352 7/20 0.44
ALOX15 P16050 3/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
TRPA1 O75762 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HSD17B10 Q99714 2/20 0.43
CHRM1 P11229 1/20 0.43
ADORA1 P30542 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SOAT1 P35610 1/20 0.42
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
CYP2D6 P10635 1/20 0.39
CYP1A2 P05177 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29926915 1.00 MGAM (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL27344077 0.86 ALDH1A1 (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL15813776 0.84 GAA (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL16341475 0.82 ALDH1A1 (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL11168976 0.82 SOAT1 (0.42) MGAMGAASIMGAM2ALDH1A1
SCHEMBL11335639 0.81 MGAM (0.52) MGAMGAASIMGAM2ALDH1A1
SCHEMBL27513497 0.81
SCHEMBL16320274 0.80 SOAT1 (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL818904 0.79
SCHEMBL819763 0.78 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1722633-B1 Use of a insecticidal composition againt mosquitoes, namely for impregnation of mosquito nets INST RECH POUR LE DÉVELOPPEMENT IRD (FR) 2014-06-18 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
US-7793920-B2 barrier against insect; the net structure made of polymer fibers is impregnated with an insecticide; preventing the low flying insects from entering open-air area; black color; invisible to certain insects VESTERGAARD SA (CH) 2010-09-14 US claimed
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US claimed
US-20070122437-A1 Novel insecticide composition and use thereof particularly for impregnating mosquito nets, fly screens and the like INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) 2007-05-31 US claimed
EP-1722633-A2 NEW INSECTICIDE COMPOSITION AND ITS USE, NAMELY FOR IMPREGNATION OF MOSQUITO NETS Institut de Recherche pour le Développement ( IRD) (FR) 2006-11-22 EP claimed
EP-1697578-A2 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-09-06 EP claimed
WO-2005079577-A2 NOVEL INSECTICIDE COMPOSITION AND USE THEREOF PARTICULARLY FOR IMPREGNATING MOSQUITO NETS, FLY SCREENS AND THE LIKE INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) 2005-09-01 WO claimed
WO-2005064072-A2 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 WO claimed
US-20050132500-A1 Composition for impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2005-06-23 US claimed
EP-1411764-A1 A FENCING Disease Control Textiles APS (DK) 2004-04-28 EP claimed
US-20040004210-A1 Fencing VESTERGAARD SA (CH) 2004-01-08 US claimed
WO-2003003827-A1 A FENCING DISEASE CONTROL TEXTILES APS (DK) 2003-01-16 WO claimed
WO-2001037662-A1 COMPOSITION FOR IMPREGNATION OF FABRICS AND NETTINGS DCT APS (DK) 2001-05-31 WO claimed
US-4900732-A Method of treating American and Oriental cockroaches BERENTER ALLEN (US) 1990-02-13 US claimed
US-4869731-A Process for the thermal decomposition of toxic refractory organic substances DYNECOLOGY, INCORPORATED (US) 1989-09-26 US claimed
US-RE32356-E Controlled release of compounds utilizing a plastic matrix Consolidated Fertilizers Limited (AU) 1987-02-17 US claimed
EP-0126827-A1 Controlled release aquatic biologically active agent formulations THE STOLLE RESEARCH AND DEVELOPMENT CORPORATION (US) 1984-12-05 EP claimed
US-4400374-A PESTICIDE DISPENSERS ENVIRONMENTAL CHEMICALS, INC. (US) 1983-08-23 US claimed
US-4228614-A Floating pesticide dispenser ENVIRONMENTAL CHEMICALS, INC. (US) 1980-10-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests GAP43, GRN, DDT MGAM 1493/4885GAA 3097/4885SI 3646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.