Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966601 | 1.00 | MME (0.56) | MMEATMPPARGPPARAMMEL1 | |
| SCHEMBL740780 | 1.00 | MME (0.56) | MMEATMPPARGPPARAMMEL1 | |
| SCHEMBL20415719 | 0.88 | ATM (0.51) | MMEATMPPARGPPARAGAA | |
| SCHEMBL28556360 | 0.88 | ATM (0.51) | MMEATMPPARGPPARAGAA | |
| SCHEMBL18262538 | 0.88 | ATM (0.49) | MMEATMPPARGPPARAMMEL1 | |
| SCHEMBL18262540 | 0.88 | ATM (0.49) | MMEATMPPARGPPARAMMEL1 | |
| SCHEMBL29163523 | 0.88 | ATM (0.56) | MMEATMPPARGPPARAAPP | |
| SCHEMBL7897952 | 0.88 | ATM (0.56) | ATMPPARGPPARAAPPCTSS | |
| SCHEMBL28132845 | 0.88 | ATM (0.60) | MMEATMAPPCTSSCTSK | |
| SCHEMBL1519889 | 0.88 | ATM (0.56) | MMEATMPPARGPPARAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |