Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20415719 | 1.00 | ATM (0.51) | ATMCACNA1BPPARGPPARAGAA | |
| SCHEMBL5966601 | 0.88 | MME (0.56) | ATMCACNA1BPPARGPPARAGAA | |
| SCHEMBL740780 | 0.88 | MME (0.56) | ATMCACNA1BPPARGPPARAGAA | |
| SCHEMBL18928694 | 0.88 | CTSS (0.54) | ATMAPPALDH1A1MAPTLMNA | |
| SCHEMBL740779 | 0.88 | MME (0.56) | ATMCACNA1BPPARGPPARAGAA | |
| SCHEMBL2617241 | 0.87 | ATM (0.51) | ATMAPPALDH1A1MAPTLMNA | |
| SCHEMBL7239876 | 0.87 | ATM (0.67) | ATMAPPALDH1A1MAPTLMNA | |
| SCHEMBL13770955 | 0.87 | ATM (0.67) | ATMAPPALDH1A1MAPTLMNA | |
| SCHEMBL6896458 | 0.87 | ATM (0.67) | ATMAPPALDH1A1MAPTLMNA | |
| SCHEMBL10301474 | 0.86 | ATM (0.50) | ATMPPARGPPARAAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |