Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410460 | 0.95 | MAPT (0.45) | KMT2ASMN1; SMN2MCOLN3MAPTGLA | |
| SCHEMBL7406093 | 0.92 | MAPT (0.47) | KMT2ASMN1; SMN2MCOLN3MAPTGLA | |
| SCHEMBL5852079 | 0.73 | PLAU (0.49) | KMT2ASMN1; SMN2MCOLN3MAPTGLA | |
| SCHEMBL30963086 | 0.68 | MAPT (0.49) | KMT2ASMN1; SMN2MCOLN3MAPTGLA | |
| SCHEMBL30963115 | 0.67 | MAPT (0.47) | KMT2ASMN1; SMN2MCOLN3MAPTGLA | |
| SCHEMBL5880406 | 0.66 | MAPT (0.65) | SMN1; SMN2MCOLN3MAPTGLAC5AR1 | |
| SCHEMBL82589 | 0.66 | MAPT (0.65) | KMT2ASMN1; SMN2MCOLN3MAPTGLA | |
| SCHEMBL26413518 | 0.66 | MAPT (0.65) | SMN1; SMN2MCOLN3MAPTGLAC5AR1 | |
| SCHEMBL7543813 | 0.66 | KMT2A (0.96) | KMT2ASMN1; SMN2MCOLN3CA12CA9 | |
| SCHEMBL7545717 | 0.66 | KMT2A (0.96) | KMT2ASMN1; SMN2MCOLN3CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994895-A1 | DIPEPTIDE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-04-26 | — | — | EP | claimed |
| WO-1999006435-A1 | DIPEPTIDE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | claimed |