SCHEMBL7408221

SCHEMBL7408221

Nc1ncnc2cc(CC(=CCN3CCNCC3=O)c3ccc(Br)o3)ccc12

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 12/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7402683 0.83 F10 (0.40) F10
SCHEMBL7405104 0.82 F10 (0.40) F10
SCHEMBL7404336 0.81 F10 (0.39) F10
SCHEMBL7373121 0.80 F10 (0.36) F10
SCHEMBL1651553 0.78 F10 (0.56) F10
Hydrochloric Acid SCHEMBL4385581 0.77 F10 (0.56) F10
SCHEMBL4397007 0.75 F10 (0.47) F10
SCHEMBL1652717 0.67 F10 (0.56) F10
SCHEMBL1652719 0.67 F10 (0.56) F10
SCHEMBL7559434 0.66 F10 (0.49) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051176-A4 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARM PROD INC (US) 2002-06-12 EP disclosed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP disclosed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO disclosed