Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.47 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1651553 | 0.90 | F10 (0.56) | F10HSP90AB1IP6K1KCNH2HRH4 | |
| Hydrochloric Acid SCHEMBL4385581 | 0.89 | F10 (0.56) | F10HSP90AB1IP6K1KCNH2HRH4 | |
| SCHEMBL4392988 | 0.78 | F10 (0.47) | F10 | |
| SCHEMBL7559434 | 0.76 | F10 (0.49) | F10KCNH2 | |
| SCHEMBL7555945 | 0.76 | F10 (0.46) | F10KCNH2 | |
| SCHEMBL14896010 | 0.75 | KCNH2 (0.57) | SCN9AKCNH2 | |
| SCHEMBL27527040 | 0.75 | F10 (0.40) | F10HSP90AB1KCNH2HRH4HRH3 | |
| SCHEMBL7408221 | 0.75 | F10 (0.41) | F10 | |
| SCHEMBL7402683 | 0.74 | F10 (0.40) | F10HSP90AB1KCNH2 | |
| SCHEMBL7542716 | 0.73 | F10 (0.56) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |