Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.59 |
| ▸ | F10 | P00742 | 5/20 | 0.59 |
| ▸ | F7 | P08709 | 3/20 | 0.59 |
| ▸ | CCND3 | P30281 | 1/20 | 0.50 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314492 | 0.93 | F10 (0.48) | F2F10F7PLAUPRSS1 | |
| SCHEMBL29730336 | 0.92 | F2 (0.71) | F2F10F7PLAUPRSS1 | |
| SCHEMBL4316759 | 0.92 | TPSAB1 (0.48) | F2F10F7PLAUPRSS1 | |
| SCHEMBL548376 | 0.85 | F2 (0.45) | F2F10F7PLAUPRSS1 | |
| SCHEMBL21067335 | 0.84 | F10 (0.61) | F2F10F7PLAUPRSS1 | |
| SCHEMBL8329299 | 0.84 | F2 (0.48) | F2F10F7PLAUPRSS1 | |
| SCHEMBL23793907 | 0.83 | F2 (0.83) | F2F10F7PLAUPRSS1 | |
| SCHEMBL250171 | 0.81 | CCND3 (0.70) | CCND3CDK6NPC1RAB9AMAPT | |
| SCHEMBL6163820 | 0.80 | F10 (0.85) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7479169 | 0.80 | F10 (0.71) | F2F10F7PLAUPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |