Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428018 | 0.91 | MEN1 (0.41) | KDM4EALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL5424906 | 0.81 | PDE4A (0.44) | KDM4EALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL5439697 | 0.81 | PDE4A (0.44) | KDM4EALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL5486201 | 0.81 | DRD2 (0.34) | KDM4EALDH1A1MAPTTP53LMNA | |
| SCHEMBL5434678 | 0.79 | KMT2A (0.53) | KDM4EALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL5198392 | 0.79 | KMT2A (0.53) | KDM4EALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL5183272 | 0.79 | KMT2A (0.53) | KDM4EALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL5486198 | 0.79 | JAK2 (0.36) | — | |
| SCHEMBL5436368 | 0.78 | PDE4A (0.56) | KMT2AMAPTLMNAMEN1SMN1; SMN2 | |
| SCHEMBL5431284 | 0.78 | PDE4A (0.56) | KMT2AMAPTLMNAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002088096-A1 | COMPOUNDS INHIBITING CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-11-07 | — | — | WO | claimed |