Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.64 |
| ▸ | TUBB | P07437 | 3/20 | 0.64 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.64 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.64 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.64 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.64 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.64 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.64 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.64 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.64 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.64 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.64 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.64 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.64 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647731 | 0.87 | PTPN1 (0.66) | CYP3A4TSHRNFKB1LMNAALOX15 | |
| SCHEMBL30873175 | 0.84 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27183000 | 0.84 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27183351 | 0.83 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27183199 | 0.83 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27182886 | 0.83 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30834848 | 0.83 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27183379 | 0.83 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31527689 | 0.83 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30872999 | 0.81 | TUBB4A (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891896-A | Tri-substituted phenyl derivatives useful as PDE IV inhibitors | CELLTECH THERAPEUTICS LTD. (GB) | 1999-04-06 | — | — | US | disclosed |