Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.67 |
| ▸ | DRD3 | P35462 | 2/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.67 |
| ▸ | GHSR | Q92847 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | HTR3A | P46098 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408994 | 0.90 | TP53 (0.63) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11851286 | 0.89 | OPRK1 (0.74) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL7409162 | 0.89 | OPRK1 (0.65) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL7413320 | 0.87 | OPRK1 (0.63) | OPRK1DRD3KCNH2GHSRHTR1A | |
| Hydrochloric Acid SCHEMBL7408744 | 0.86 | OPRK1 (0.62) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11851988 | 0.85 | OPRK1 (0.74) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11847038 | 0.85 | OPRK1 (0.67) | OPRK1DRD3KCNH2GHSRHTR1A | |
| Desalkylflurazepam SCHEMBL8124276 | 0.85 | OPRK1 (0.76) | OPRK1DRD3KCNH2GHSRHTR1A | |
| Desalkylflurazepam SCHEMBL31365163 | 0.85 | OPRK1 (0.76) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11679711 | 0.84 | OPRK1 (0.74) | OPRK1DRD3KCNH2GHSRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989829-A | 1,4-Benzodiazepines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-02 | — | — | US | claimed |
| US-3989829-A | 1,4-Benzodiazepines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-02 | — | — | US | disclosed |