Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408555 | 0.81 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7009876 | 0.79 | PDE4A (0.46) | PIK3CDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7015228 | 0.79 | PDE4A (0.51) | PIK3CDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7011671 | 0.78 | PDE4A (0.52) | PIK3CDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7015082 | 0.77 | MAPT (0.45) | PIK3CDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7016954 | 0.76 | PDE4A (0.61) | PIK3CDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7016905 | 0.74 | MAPT (0.43) | PIK3CDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7016046 | 0.73 | PDE4A (0.54) | PIK3CDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7015963 | 0.72 | PDE4A (0.55) | PIK3CDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7013236 | 0.72 | PDE4A (0.55) | PIK3CDMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086106-A1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | Darwin Discovery Limited (GB) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064423-A1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | DARWIN DISCOVERY LIMITED (GB) | 1999-12-16 | — | — | WO | disclosed |