Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094443 | 0.86 | MAPT (0.50) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7410481 | 0.84 | ALDH1A1 (0.53) | HTTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL10616161 | 0.83 | POLB (0.44) | HTTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL10614757 | 0.71 | MEN1 (0.46) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL25229553 | 0.67 | ALDH1A1 (0.63) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14181847 | 0.67 | KMT2A (0.69) | HTTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11123393 | 0.66 | RXFP1 (0.59) | HTTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL654734 | 0.66 | RXFP1 (0.54) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9844929 | 0.66 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11081671 | 0.66 | ALDH1A1 (0.48) | HTTALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000651-A2 | FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |