Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376207 | 0.85 | AAK1 (0.64) | TAAR1MMEACEAAK1MEN1 | |
| SCHEMBL7376209 | 0.85 | AAK1 (0.64) | TAAR1MMEACEAAK1MEN1 | |
| SCHEMBL11784661 | 0.85 | GAA (0.53) | TAAR1MMEACEAAK1MEN1 | |
| Hydrochloric Acid SCHEMBL10788646 | 0.84 | AAK1 (0.62) | TAAR1MMEACEAAK1MEN1 | |
| Acetic Acid SCHEMBL8935166 | 0.83 | AAK1 (0.61) | TAAR1MMEACEAAK1MEN1 | |
| Hydrochloric Acid SCHEMBL10846536 | 0.79 | LTA4H (0.52) | TAAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3954076 | 0.78 | LTA4H (0.67) | TAAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5270163 | 0.78 | MEN1 (0.60) | TAAR1MMEACEMEN1KMT2A | |
| SCHEMBL10791327 | 0.78 | MEN1 (0.60) | TAAR1MMEACEMEN1KMT2A | |
| SCHEMBL14209990 | 0.78 | MEN1 (0.60) | TAAR1MMEACEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403952-A | Substituted cyclic derivatives as novel antidegenerative agents | MERCK & CO., INC. (US) | 1995-04-04 | — | — | US | disclosed |