Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.50 |
| ▸ | PARP1 | P09874 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724307 | 0.84 | TRPA1 (0.35) | TRPA1ALDH1A1 | |
| SCHEMBL7335586 | 0.74 | PARP1 (0.42) | TRPA1PARP1KDM4EALDH1A1MAPT | |
| SCHEMBL17766590 | 0.69 | PARP1 (0.47) | TRPA1PARP1KDM4EALDH1A1MAPT | |
| SCHEMBL13098173 | 0.67 | TRPA1 (1.00) | TRPA1PARP1MAPT | |
| SCHEMBL22612514 | 0.66 | PARP1 (0.44) | TRPA1PARP1KDM4EALDH1A1MAPT | |
| SCHEMBL29501123 | 0.66 | TSHR (0.42) | PARP1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL29501144 | 0.66 | PIM1 (0.34) | ALDH1A1 | |
| SCHEMBL7379312 | 0.65 | PARP1 (0.42) | TRPA1PARP1KDM4EALDH1A1MAPT | |
| SCHEMBL5322268 | 0.65 | PARP1 (0.54) | TRPA1PARP1KDM4EALDH1A1MAPT | |
| SCHEMBL13098214 | 0.63 | TRPA1 (1.00) | TRPA1PARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |