Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.45 |
| ▸ | F7 | P08709 | 15/20 | 0.45 |
| ▸ | F3 | P13726 | 13/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.45 |
| ▸ | F2 | P00734 | 11/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883027 | 0.93 | F10 (0.47) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5882844 | 0.90 | F7 (0.45) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5882377 | 0.89 | F7 (0.58) | F10F7F3PRSS1PRSS2 | |
| Acetic Acid SCHEMBL5883161 | 0.88 | F7 (0.56) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL7414259 | 0.87 | F10 (0.43) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL7414799 | 0.85 | F10 (0.50) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL7144834 | 0.85 | F10 (0.45) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL7144841 | 0.85 | F10 (0.45) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL27573411 | 0.84 | F10 (0.44) | F10F7F3PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7141543 | 0.83 | F10 (0.43) | F10F7F3PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |