Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.50 |
| ▸ | F7 | P08709 | 15/20 | 0.50 |
| ▸ | F3 | P13726 | 13/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.50 |
| ▸ | F2 | P00734 | 12/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415363 | 0.91 | F10 (0.49) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5883023 | 0.89 | F10 (0.64) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5883027 | 0.88 | F10 (0.47) | F10F7F3PRSS1PRSS2 | |
| Acetic Acid SCHEMBL5883782 | 0.87 | F10 (0.62) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5882703 | 0.87 | F10 (0.54) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL7410198 | 0.85 | F10 (0.45) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5882514 | 0.84 | F10 (0.43) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL7144834 | 0.83 | F10 (0.45) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL7144841 | 0.83 | F10 (0.45) | F10F7F3PRSS1PRSS2 | |
| SCHEMBL5882844 | 0.83 | F7 (0.45) | F10F7F3PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |